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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are typically described as focusing on practical aspects of study design, including recruitment and consent, adherence and 프라그마틱 슬롯 무료체험 the use routinely available equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and participants from various geographical areas. This type of heterogeneity is required for pragmatic trials to be able to prove their validity, and it also reduces the chance of bias in the results. Too much heterogeneity, however can result in problems with the trial design.

Pragmatic Play is also a major player on the live casino market, providing an array of classic table games such as Blackjack and Roulette in a variety of versions. The live studios of the company in Romania and Malta provide customers with an authentic experience in gambling as well as a broad variety of betting options via virtual. The company also hosts a variety of games that make online gambling exciting and interactive. Some of these shows feature live hosts, while others are hosted by famous personalities from the industry.

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Pragmatic trials are designed to replicate real-life settings and achieve maximum external validity. They are usually requested by practitioners and policy makers to aid in their decision-making. They can be used to determine the causality of an intervention with its outcomes. However, they should not be used to substitute for explanation trials.

The idea of pragmatism is controversial and there are doubts about whether pragmatic trials should replace explanatory tests or if they should be an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which validate a physiological or clinical hypothesis as well as pragmatic trials, which inform the policy and practice of. They also suggested the framework for pragmatic trials, called PRECIS.2 This tool sought to define the elements of a practical trial, including the recruitment process, the design and implementation of the intervention, and follow-up.

The number of pragmatic trials is growing. A recent Medline search using the keywords pragmatic and naturalistic, restricted to controlled trials that are randomized (RCTs) resulted in 34 articles, which are shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. However, it is important to remember that the majority of these studies were conducted in primary care settings.